Analysis of Deterministic Cyclic Gene Regulatory Network Models with Delays (Record no. 53098)
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fixed length control field | 03264nam a22005895i 4500 |
001 - CONTROL NUMBER | |
control field | 978-3-319-15606-4 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20200420221259.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 150225s2015 gw | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
ISBN | 9783319156064 |
-- | 978-3-319-15606-4 |
082 04 - CLASSIFICATION NUMBER | |
Call Number | 519 |
100 1# - AUTHOR NAME | |
Author | Ahsen, Mehmet Eren. |
245 10 - TITLE STATEMENT | |
Title | Analysis of Deterministic Cyclic Gene Regulatory Network Models with Delays |
300 ## - PHYSICAL DESCRIPTION | |
Number of Pages | XIII, 94 p. 15 illus. in color. |
490 1# - SERIES STATEMENT | |
Series statement | SpringerBriefs in Electrical and Computer Engineering, |
505 0# - FORMATTED CONTENTS NOTE | |
Remark 2 | Preface -- Introduction -- Basic Tools from Systems and Control Theory -- Functions with Negative Schwarzian Derivatives -- Deterministic ODE-Based Model with Time Delay -- Gene Regulatory Networks under Negative Feedback -- Gene Regulatory Networks under Positive Feedback -- Summary and Concluding Remarks -- References. |
520 ## - SUMMARY, ETC. | |
Summary, etc | This brief examines a deterministic, ODE-based model for gene regulatory networks (GRN) that incorporates nonlinearities and time-delayed feedback. An introductory chapter provides some insights into molecular biology and GRNs. The mathematical tools necessary for studying the GRN model are then reviewed, in particular Hill functions and Schwarzian derivatives. One chapter is devoted to the analysis of GRNs under negative feedback with time delays and a special case of a homogenous GRN is considered. Asymptotic stability analysis of GRNs under positive feedback is then considered in a separate chapter, in which conditions leading to bi-stability are derived. Graduate and advanced undergraduate students and researchers in control engineering, applied mathematics, systems biology and synthetic biology will find this brief to be a clear and concise introduction to the modeling and analysis of GRNs. |
700 1# - AUTHOR 2 | |
Author 2 | �Ozbay, Hitay. |
700 1# - AUTHOR 2 | |
Author 2 | Niculescu, Silviu-Iulian. |
856 40 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-319-15606-4 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Koha item type | eBooks |
264 #1 - | |
-- | Cham : |
-- | Springer International Publishing : |
-- | Imprint: Birkh�auser, |
-- | 2015. |
336 ## - | |
-- | text |
-- | txt |
-- | rdacontent |
337 ## - | |
-- | computer |
-- | c |
-- | rdamedia |
338 ## - | |
-- | online resource |
-- | cr |
-- | rdacarrier |
347 ## - | |
-- | text file |
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-- | rda |
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Mathematics. |
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Gene expression. |
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | System theory. |
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Biomathematics. |
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Control engineering. |
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Robotics. |
650 #0 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Mechatronics. |
650 14 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Mathematics. |
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Systems Theory, Control. |
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Mathematical and Computational Biology. |
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Gene Expression. |
650 24 - SUBJECT ADDED ENTRY--SUBJECT 1 | |
-- | Control, Robotics, Mechatronics. |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
-- | 2191-8112 |
912 ## - | |
-- | ZDB-2-ENG |
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