000 03382nam a22004815i 4500
001 978-3-319-11403-3
003 DE-He213
005 20200421111659.0
007 cr nn 008mamaa
008 140924s2015 gw | s |||| 0|eng d
020 _a9783319114033
_9978-3-319-11403-3
024 7 _a10.1007/978-3-319-11403-3
_2doi
050 4 _aQ342
072 7 _aUYQ
_2bicssc
072 7 _aCOM004000
_2bisacsh
082 0 4 _a006.3
_223
100 1 _aSingh, Gautam B.
_eauthor.
245 1 0 _aFundamentals of Bioinformatics and Computational Biology
_h[electronic resource] :
_bMethods and Exercises in MATLAB /
_cby Gautam B. Singh.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aXVI, 339 p. 106 illus., 9 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aModeling and Optimization in Science and Technologies,
_x2196-7326 ;
_v6
505 0 _aBackground -- Biological Database Retrieval -- Biological Sequence Analysis.-Phylogenetics and Systems Biology.
520 _aThis book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolbox™. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today's biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.  .
650 0 _aEngineering.
650 0 _aBioinformatics.
650 0 _aComputational intelligence.
650 1 4 _aEngineering.
650 2 4 _aComputational Intelligence.
650 2 4 _aComputational Biology/Bioinformatics.
650 2 4 _aBioinformatics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319114026
830 0 _aModeling and Optimization in Science and Technologies,
_x2196-7326 ;
_v6
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-11403-3
912 _aZDB-2-ENG
942 _cEBK
999 _c54912
_d54912