000 | 03344nam a22005415i 4500 | ||
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001 | 978-3-319-69059-9 | ||
003 | DE-He213 | ||
005 | 20220801214034.0 | ||
007 | cr nn 008mamaa | ||
008 | 171115s2018 sz | s |||| 0|eng d | ||
020 |
_a9783319690599 _9978-3-319-69059-9 |
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024 | 7 |
_a10.1007/978-3-319-69059-9 _2doi |
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050 | 4 | _aR856-857 | |
072 | 7 |
_aMQW _2bicssc |
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_aTEC059000 _2bisacsh |
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_aMQW _2thema |
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_a610.28 _223 |
100 | 1 |
_aTay, Andy Kah Ping. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut _935938 |
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245 | 1 | 0 |
_aAcute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels _h[electronic resource] / _cby Andy Kah Ping Tay. |
250 | _a1st ed. 2018. | ||
264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2018. |
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300 |
_aXVII, 119 p. 33 illus., 32 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5061 |
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505 | 0 | _aMicro- and Nano-Technologies to Probe Brain Mechanobiology -- Acute Neural Stimulation -- Chronic Neural Stimulation -- Phenotypic Selection of Magnetospirillum magneticum (AMB-1) Over-Producers using Magnetic Ratcheting -- Magnetic Microfluidic Separation for Estimating the Magnetic Contents of Magnetotactic Bacteria -- Outlook for Magnetic Neural Stimulation Techniques. . | |
520 | _aThis book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms—magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria—that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation. | ||
650 | 0 |
_aBiomedical engineering. _93292 |
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650 | 0 |
_aNanotechnology. _94707 |
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650 | 0 |
_aNanoscience. _910727 |
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650 | 1 | 4 |
_aBiomedical Engineering and Bioengineering. _931842 |
650 | 2 | 4 |
_aNanotechnology. _94707 |
650 | 2 | 4 |
_aNanophysics. _932302 |
710 | 2 |
_aSpringerLink (Online service) _935939 |
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773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9783319690582 |
776 | 0 | 8 |
_iPrinted edition: _z9783319690605 |
776 | 0 | 8 |
_iPrinted edition: _z9783319887081 |
830 | 0 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5061 _935940 |
|
856 | 4 | 0 | _uhttps://doi.org/10.1007/978-3-319-69059-9 |
912 | _aZDB-2-ENG | ||
912 | _aZDB-2-SXE | ||
942 | _cEBK | ||
999 |
_c75889 _d75889 |