000			04994cam a2200577 a 4500
001			on1190859379
003			OCoLC
005			20230516165905.0
006			m o d
007			cr |n|||||||||
008			200828s2020 ne o 001 0 eng d
040			_aYDX _beng _epn _cYDX _dOPELS _dEBLCP _dUKAHL _dUKMGB _dOCLCF _dOCLCO _dOCLCQ _dK6U _dOCLCQ
015			_aGBC0B7107 _2bnb
016	7		_a019886921 _2Uk
020			_a9780128178393 _q(electronic bk.)
020			_a0128178396 _q(electronic bk.)
020			_z9780128178386
020			_z0128178388
035			_a(OCoLC)1190859379
050		4	_aTA418.9.N35
082	0	4	_a620.1/15 _223
245	0	0	_aNanomaterials for theranostics and tissue engineering : _btechniques, trends and applications / _cedited by Filippo Rossi and Alberto Rainer.
260			_aAmsterdam : _bElsevier, _c2020.
300			_a1 online resource
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aMicro and Nano Technologies
500			_aIncludes index.
505	0		_aFront Cover -- Nanomaterials for Theranostics and Tissue Engineering -- Copyright Page -- Contents -- List of contributors -- Introduction -- 1 Polymeric nanoparticles for controlled drug delivery -- 1.1 General concepts and synthetic strategies -- 1.2 Polymer nanoparticles for controlled drug delivery -- 1.2.1 Stimuli-responsive polymer nanoparticles -- 1.3 The long road from the bench to the clinic -- 1.4 Conclusions -- References -- 2 Extracellular vesicles in regenerative medicine -- 2.1 Introduction -- 2.2 Cell-based therapies -- 2.3 Tissue engineering -- 2.4 Cell-free therapies
505	8		_a2.4.1 Soluble factors -- 2.4.2 Biogenic and synthetic nanoparticles -- 2.5 Extracellular vesicles in a nutshell -- 2.5.1 Extracellular vesicle biological and physicochemical properties -- 2.5.2 Extracellular vesicle separation and characterization -- 2.5.3 Medical translation of extracellular vesicles -- 2.6 Regenerative properties of extracellular vesicles -- 2.6.1 Why extracellular vesicles? -- 2.6.2 Preclinical studies -- 2.6.3 Clinical studies -- 2.6.4 Limits of extracellular vesicle applications in clinical treatments -- 2.7 Conclusions -- Acknowledgments -- References
505	8		_a3 Novel strategies to improve delivery performances -- 3.1 Introduction -- 3.2 Functionalization strategies: the rationale -- 3.2.1 Chemical routes -- 3.2.1.1 Esterification and modification of active ester -- 3.2.1.2 Click chemistry -- 3.2.1.3 Other chemical cross-linking strategies -- 3.2.2 Physical routes -- 3.3 Applications in tissue engineering -- 3.3.1 The cell membranes barrier -- 3.3.2 The tumor environment -- 3.3.3 The blood-brain barrier -- 3.4 Applications in theranostics -- 3.5 Conclusions -- References -- 4 HR-MAS NMR Spectroscopy: novel technologies to measure delivery performance
505	8		_a4.1 Introduction -- 4.2 High-resolution magic angle spinning nuclear magnetic resonance -- 4.2.1 Theory -- 4.2.2 Experimental setup -- 4.2.3 Example HR-MAS resolution enhancement in hydrogel polymers and swollen polymers -- 4.3 Pulse field gradient HR-MAS nuclear magnetic resonance spectroscopy -- 4.3.1 Translational motion in isotropic systems -- 4.3.2 Restricted and anisotropic motion -- 4.4 Applications in drug delivery -- 4.4.1 Cyclodextrin nanosponges polymers -- 4.4.2 Agarose-carbomer copolymers hydrogels -- 4.5 Final remarks -- References
505	8		_a5 The role of first principles mathematical modeling in the nanomedicine field -- 5.1 The new challenges introduced by nanomedicine -- 5.2 Modeling approaches -- 5.2.1 An introduction to molecular modeling -- 5.2.2 Molecular dynamics -- 5.2.3 Coarse-grained simulations -- 5.2.4 Enhanced sampling methods -- 5.2.5 Macroscale models -- 5.3 Applications of mathematical modeling in the nanomedicine field -- 5.3.1 Biomolecular corona -- 5.3.2 Targeting and cellular uptake -- 5.3.3 Nanoparticle distribution and drug delivery -- 5.4 Conclusions -- References
650		0	_aNanostructured materials. _94537
650		0	_aNanomedicine. _95252
650		0	_aTissue engineering. _93291
650		2	_aNanostructures _0(DNLM)D049329 _95928
650		2	_aTissue Engineering _0(DNLM)D023822 _93291
650		6	_aNanomat�eriaux. _0(CaQQLa)201-0258061 _968453
650		6	_aG�enie tissulaire. _0(CaQQLa)201-0392445 _968656
650		7	_aNanomedicine _2fast _0(OCoLC)fst01744350 _95252
650		7	_aNanostructured materials _2fast _0(OCoLC)fst01032630 _94537
650		7	_aTissue engineering _2fast _0(OCoLC)fst01151484 _93291
700	1		_aRossi, Filippo. _968897
700	1		_aRainer, Alberto. _968898
776	0	8	_iPrint version: _tNanomaterials for theranostics and tissue engineering. _dAmsterdam : Elsevier, 2020 _z0128178388 _z9780128178386 _w(OCoLC)1122909371
830		0	_aMicro & nano technologies. _968899
856	4	0	_3ScienceDirect _uhttps://www.sciencedirect.com/science/book/9780128178386
942			_cEBK
999			_c82481 _d82481